Review Article
Enterococcus faecalis in Oral Infections
1Discipline of Endodontics, Department of Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil
2Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
- Corresponding Author:
- Ericka Tavares Pinheiro
Department of Dentistry, School of Dentistry
University of São Paulo, Av. Lineu Prestes
2227, São Paulo, SP, 05508-000, Brazil
Tel: 55-11-3091-7839/202
Fax: 55-11-3091-7839
E-mail: erickapinheiro@usp.com
Received date July 16, 2014; Accepted date November 21, 2014; Published date November 24, 2014
Citation: Pinheiro ET, Mayer MPA (2015) Enterococcus faecalis in Oral Infections. J Interdiscipl Med Dent Sci 3:160. doi: 10.4172/2376-032X.1000160
Copyright: © 2015 Pinheiro ET, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Enterococcus faecalis is a member of the normal microbiota; however, multidrug-resistant strains are important causes of nosocomial infections. Their ability to cause serious infections has been linked to variable traits that enhance their virulence. In the oral cavity, E. faecalis is commonly detected from root canals of teeth with post-treatment apical periodontitis or refractory/advanced marginal periodontitis. Isolates from oral infections have a genetic and virulence profile different from hospital-derived isolates. This Review discusses the occurrence of E. faecalis in oral infections, and the virulence factors that may contribute to the pathogenesis of post-treatment apical and marginal periodontitis. The susceptibility patterns of oral E. faecalis to various antibiotics of potential use in periodontal and endodontic therapy are also reviewed.