ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
Open Access

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
  • Research Article   
  • J Infect Dis Ther,
  • DOI: 10.4172/2332-0877.1000560

Elevated Methaemoglobin Level in COVID-19 Patients in Intensive Care Unit

Zaid Khalid1, Vásárhelyi Barna2 and Zoltan Vajda2*
1Department of Intensive Care Unit, Almási Balogh Pál City Hospital, Ózd, Hungary
2Department of Laboratory Medicine, University Medical School, Budapest, Hungary
*Corresponding Author : Dr. Zoltan Vajda, Department of Laboratory Medicine, University Medical School, Budapest, Hungary, Email: vajda.zoltan@med.semmelweisuniv.hu

Received Date: Aug 03, 2023 / Published Date: Sep 04, 2023

Abstract

There have been reports that methaemoglobin levels are raising in COVID-19 patients.

Methods: The diagnosis of Coronavirus-19 infection was confirmed by RT-PCR. The methaemoglobin determination was by cyanidderivative spectrophotometry.

Results: There were altogether 46 patients (11 male, 35 female) included. Their median age was 70 y. ( 29-89). The methaemoglobin median value was 3,9 15 of 46 patients died. The methaemoglobin median value of departed patients was 8%, and 2,5% was among survivors. ( p=0,001).19 patients were blood transfused. Their methaemoglobin median was 11%, otherwise the non transfused patients presented 2,7% methaemoglobin median.(p=0,001).We performed two binary logistic regression calculation, computing the elevated methaemoglobin level as an independent risk factor for the mortality. The predictor of methaemoglobin was 0,062 the constant -1,266 the odds ratio 1,06. The other binary logistic regression tested the fact of transfusion for the mortality. Predictor of transfusion 1,1474, constant -1,2527 odds ratio 3,15.

Conclusion: The correlation of methaemoglobin with mortality is worth examining further. The role of transfusion is obscure, because the methaemoglobin can be elevated in blood conserves during storage. Testing the methemoglobin seems to be important, but the pathomechanism needs further research.

Keywords: COVID-19; Methaemoglobin level; Transfusion; Mortality

Citation: Khalid Z, Barna V, Vajda Z (2023) Elevated Methaemoglobin Level in COVID-19 Patients in Intensive Care Unit. J Infect Dis Ther 11:560. Doi: 10.4172/2332-0877.1000560

Copyright: © 2023 Khalid Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Top