Abstract

Epilepsy is a neurological disorder characterized by recurrent seizures that affect millions of people worldwide. The primary treatment for epilepsy involves the administration of anti-seizure medications (ASMs). However, the effectiveness of ASMs can be influenced by various factors, including diet. This dissertation explores the effects of different diets on the metabolism of ASMs and their implications for the treatment of epilepsy. The research aims to provide insights into the interactions between diet, drug metabolism, and seizure control, ultimately contributing to the development of personalized treatment strategies for individuals with epilepsy. The treatment of epilepsy often involves the use of anti-seizure medications (ASMs) to control seizure activity and improve quality of life. However, the metabolism of ASMs can be influenced by various factors, including diet. This dissertation aims to explore the effects of diet on the metabolism of ASMs and its implications for the treatment of epilepsy. To assess the clinical implications of diet-drug interactions in the context of epilepsy treatment. To explore potential strategies for personalized medicine in epilepsy, considering dietary modifications and therapeutic drug monitoring.

Keywords: Drug Metabolizing enzymes; Plasmodium berghei; Plasmodium habaudi; Plasmodium falciparum