Abstract

Objective: to evaluate the impact of Oral Supplementation with iron sulphate (with liposomal vitamin C) in pregnant women to treat iron deficiency anemia.
Methods: This was an observational retrospective study. Women who received oral supplementation with oral iron sulphate (with liposomal vitamin C) as treatment for iron deficiency anemia were compared with women who did not. Inclusion criteria were singleton gestations with microcytic mild iron deficiency anemia. Mild anemia was defined as Hgb level between 9.00 and 10.99 g/dL. The primary outcome of the study was the incidence of anemia after treatment. The secondary outcomes were rise in serum ferritin, rise in Hgb level and maternal tolerability.
Results: 200 women, 100 for each group, were included in the study. Women who received the intervention had a significantly lower overall incidence of anemia after 2 months, and at post-partum follow-up visit. Moreover, rise in Hgb level and serum ferritin were significantly higher in the intervention.
Conclusion: Our retrospective cohort of singleton gestations with mild anemia in pregnancy showed that oral supplementation with iron sulphate (with liposomal vitamin C) as treatment for iron deficiency anemia was a safe and efficacy treatment to reduce the recurrence of anemia.