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Hindi Early onset infantile ulcerative colitis: A rare atypical aetiology of toddler's diarrhea
*Corresponding Author: Dr. Mithilesh Kumar, Department of Paediatrics, Max Super speciality Hospital, New Delhi, India, Tel: +91-7678487949, Email: drmith2010@gmail.comReceived Date: Feb 10, 2020 /
Citation: Kumar M, Kumar D, Sachan D, Ahuja A (2020) Early onset infantile ulcerative colitis: A rare atypical aetiology of toddler’s diarrhea. J Gastrointest Dig Syst 10: 616.
Copyright: © 2020 Kumar M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Introduction: Paediatric IBD is a chronic inflammatory disease characterised with complex interaction of genetic, environmental and mucosal immune response regulating factors. Paediatric IBD has mean age of presentation of 12 years with very early IBD as a rare presentation having less than 1 % incidence. Early IBD shows predominance of incidence of CD over UC. Paediatric UC occasionally presents features of macroscopic rectal sparing.
Case report: This is case report of early IBD with atypical features of macroscopic and microscopic rectal sparing. Toddler presented with bloody diarrhoea, failure to thrive, skin rash and swollen knee. On examination baby was severely wasting with stunting, severe pallor and multiple skin lesion over leg. Bilateral knee arthritis with restriction of movement also was observed in baby. Patient was diagnosed as UC on basis of colonoscopy and histology. Absence of perianal disease, stenosis, cobble stoning, and linear ulcerations in the ileum ruled out CD. Infectious colitis, Allergy and immunodeficiency disorder most often implicated in causes of infantile colitis were differentially ruled out.
Conclusion: Infantile disease is more frequently associated with a CD-type illness, but distinguishing between CD and UC is challenging. And the diagnosis may change during subsequent follow up.
