Diabetes and Mitochondrial Fission and Fusion Dynamics
Received Date: Apr 13, 2022 / Accepted Date: May 06, 2022 / Published Date: May 11, 2022
Abstract
Mitochondria are biosynthetic, bioenergetics and signaling organelle that regulates cellular and organism homeostasis in variety of ways. Mitochondrial dysfunction, a high generation of reactive oxygen species (ROS), and low level ATP are all symptoms of type 2 diabetes. Mitofusion-1, 2 and optic atrophy regulate mitochondrial fusion, whereas Mitochondrial fission 1, dynamic related protein 1 and mitochondrial fission regulate mitochondrial fission. PARKIN and PTEN-induced putative Kinase 1 are involved in the mitophagy process. In this review, we discuss about molecular pathways of mitochondrial dynamics in type 2 diabetes.
Citation: Bagga T (2022) Diabetes and Mitochondrial Fission and Fusion Dynamics. J Mol Pharm Org Process Res 10: 135. Doi: 10.4172/2329-9053.1000135
Copyright: © 2022 Bagga T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Share This Article
Recommended Journals
Open Access Journals
Article Tools
Article Usage
- Total views: 1592
- [From(publication date): 0-2022 - Dec 19, 2024]
- Breakdown by view type
- HTML page views: 1253
- PDF downloads: 339
