Abstract

Liposomal nanocarriers have emerged as a promising platform for targeted drug delivery due to their biocompatibility, ability to encapsulate various types of therapeutic agents, and potential for functionalization with targeting ligands. This article provides a comprehensive overview of the design and characterization of liposomal nanocarriers. We discuss the various methods of liposome preparation, the physicochemical properties critical to their performance, and the strategies for functionalization and targeting. Additionally, we explore the current methodologies for the characterization of liposomes, including size distribution, surface charge, drug encapsulation efficiency, and in vitro and in vivo stability. The potential of liposomal nanocarriers in improving the therapeutic index of drugs is highlighted through case studies and recent advancements in the field.