Abstract

Cytokine therapy represents a promising frontier in cancer treatment, leveraging the body’s immune system to combat tumors through targeted immunomodulation. This abstract provides an overview of cytokine therapy’s potential in cancer treatment, elucidating its mechanisms of action, clinical applications, and future directions. Cytokines, such as interleukins and interferons, stimulate immune responses, inhibit tumor angiogenesis, and modulate the tumor microenvironment. Clinical applications include the treatment of renal cell carcinoma, melanoma, and hematological malignancies, with notable successes in achieving durable responses. Despite challenges like systemic toxicity and limited efficacy in certain tumors, ongoing research focuses on targeted delivery systems, combination therapies, and personalized approaches to optimize treatment outcomes. With its multifaceted mechanisms and evolving strategies, cytokine therapy stands at the forefront of cancer treatment, offering new avenues for improving patient outcomes and advancing the fight against cancer.