Cytokine Release Syndrome: Causes, Symptoms and Treatmen
Received Date: Mar 01, 2024 / Accepted Date: Mar 29, 2024 / Published Date: Mar 29, 2024
Abstract
Cytokine Release Syndrome (CRS) is a systemic inflammatory response characterized by the rapid release of pro-inflammatory cytokines into the bloodstream. It can occur in response to various triggers, including immunotherapy, infections, and certain medications. CRS is most commonly associated with immunotherapeutic treatments such as CAR T-cell therapy and BiTE therapy, where an overactive immune response can lead to severe complications. Clinical manifestations of CRS range from mild flu-like symptoms to life-threatening multi-organ dysfunction. Diagnosis typically involves clinical assessment, laboratory tests, and imaging studies to evaluate organ function and detect complications. Treatment strategies focus on controlling inflammation, supportive care, and addressing the underlying cause. This abstract provides an overview of CRS, highlighting the importance of early recognition and intervention in managing this potentially serious condition. Further research is needed to improve our understanding of CRS pathophysiology and develop more effective prevention and treatment strategies.
Citation: Gail H (2024) Cytokine Release Syndrome: Causes, Symptoms andTreatment. J Cytokine Biol 9: 498.
Copyright: © 2024 Gail H. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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