Abstract

Cystic fibrosis (CF) is a genetic disorder characterized by the production of thick and sticky mucus in the respiratory, digestive, and reproductive systems. Early diagnosis is crucial for initiating timely treatment and improving outcomes. Newborn screening programs, genetic testing, and sweat chloride testing are instrumental in identifying individuals with CF. Treatment strategies focus on maintaining lung function, preventing infections, managing digestive issues, and providing nutritional support through a multidisciplinary approach. Airway clearance techniques, bronchodilators, antibiotics, and nutritional supplements are key components of CF management. Recent advancements in CF research have led to the development of targeted therapies, such as CFTR modulators, which improve CFTR function and reduce disease progression. Ongoing research efforts aim to develop next-generation CFTR modulators, gene editing techniques, and novel therapies to address inflammation, infection, and mucus clearance in CF. Despite the complexities of CF, advancements in diagnosis, treatment, and research offer hope for improved outcomes and quality of life for individuals living with this condition. A multidisciplinary approach that combines medical management with ongoing research efforts is essential for advancing towards a cure for CF.