Abstract

Colposcopy-directed biopsy is a cornerstone in the clinical management of HPV-positive women, offering critical insights into cervical abnormalities and guiding treatment decisions. This article explores the clinical considerations surrounding colposcopy-directed biopsy in HPV-positive women, focusing on its role in detection, assessment, and therapeutic interventions. Key aspects include the identification of cervical lesions, biopsy techniques, histopathological evaluation, and implications for treatment planning. Challenges and future directions in improving diagnostic accuracy and patient outcomes are also discussed, highlighting the evolving landscape of cervical cancer prevention and management.