Abstract

Urinary tract infections (UTIs) caused by Escherichia coli (E. coli) are a pervasive global health issue, presenting clinical challenges due to antibiotic resistance. This article explores clinical perspectives on E. coli UTIs and innovative treatment approaches. Traditional antibiotics, once effective, are facing increasing resistance. Innovative solutions, including fosfomycin, phage therapy, vaccines, probiotics, CRISPR-based therapies, and nanotechnology, offer potential breakthroughs. A patient-centered approach, coupled with prevention strategies, is essential in E. coli UTI management. These innovative treatments represent promising advancements in the field, highlighting the potential for more effective solutions to combat E. coli UTIs.