JBR Journal of Clinical Diagnosis and Research
Open Access

Research Article

Clinical Outcome for PVL+ Staphylococcus aureus Associated Necrotising Pneumonia may be Optimised Through Combination of Prompt Antimicrobial and Anti-Toxin Treatment

Tom Marrs^1,2* and Colin Michie³

¹Children’s Allergies, Evelina Children’s Hospital, St Thomas’ Hospital, Westminster Bridge Road, London, UK

²Division of Asthma, Allergy and Lung Biology, King’s College London, UK

³Department of Paediatrics, Ealing Hospital, London, UK

Corresponding Author:

Marrs T
Children’s Allergies, Evelina Children’s Hospital
St Thomas’ Hospital, Westminster Bridge Road, London, UK
Tel: +44 (0) 20 7188 4877
Fax: +44 (0) 20 7188 978
E-mail: tommarrs@doctors.org.uk

Received date: March 19, 2014; Accepted date: August 25, 2014; Published date: September 02, 2014

Citation: Marrs T, Michie C (2014) Clinical Outcome for PVL+ Staphylococcus Aureus Associated Necrotising Pneumonia may be Optimised Through Combination of Prompt Antimicrobial and Anti-Toxin Treatment. J Clin Diagn Res 2:108. doi:10.4172/2376-0311.1000108

Copyright: © 2014 Marrs T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Necrotising pneumonia caused by Panton-Valentine Leukocidin Staphylococcus aureus confers a high mortality. We describe a child presenting with sepsis and necrotising pneumonia. Septicaemia caused by Panton-Valentine Leukocidin Staphylococcus may not be adequately treated with antibiotics to which it appears sensitive through standard culture techniques. Some evidence suggests that early anti-toxin therapy may better optimise clinical outcomes.

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