Abstract

Problems of diagnosis of hypoxic-ischemic encephalopathy in preterm neonates remain relevant, serious and not fully studied and not fully refined directions.

The revealed regularities and peculiarities depending on the gestational age of newborns allows as to assert that applied immune-fermentative studies for the diagnosis of hypoxic-ischemic encephalopathy show that they need further improvment, and instrumental methods are not allowed to have an early and clear understending about the prevalence of pathological process, predict outcome and to develop therapeutic tactics.

Keywords: Hypoxic-ischemic encephalopathy; Neuron specific markers; Periventricular leukomalacia; Central nervous system