Abstract

Fungal infections represent a substantial global health concern, affecting a diverse range of individuals, from those with superficial skin conditions to those with life-threatening systemic diseases. The emergence of antifungal resistance has added a new layer of complexity to this issue. This abstract explores the challenges posed by antifungal resistance in the context of fungal infections. We discuss the limited availability of antifungal medications, inadequate diagnostics, inappropriate antifungal use, environmental and host factors, and the need for innovative strategies to address this growing concern. Antifungal stewardship, enhanced diagnostics, combination therapies, fungal genomics, and environmental monitoring are proposed as key strategies to combat resistance. The pressing need for collaborative efforts, research, and investments in this area is highlighted, emphasizing the importance of safeguarding effective treatments for fungal infections.