Abstract

Cellular drug uptake is a critical process in pharmacology that determines the efficacy and safety of therapeutic agents. The ability of a drug to enter a cell is influenced by its chemical properties, the type of cell, and the transport mechanisms available. Understanding the mechanisms of cellular drug uptake is essential for developing more effective and targeted therapies, particularly for diseases like cancer, neurological disorders, and infections. This article reviews the key mechanisms involved in cellular drug uptake, the factors affecting drug entry, and the challenges faced in drug delivery. It also explores the implications of cellular drug uptake in the design of novel drug delivery systems and personalized medicine.