Abstract

Capillary electrophoresis (CE) has emerged as a powerful analytical technique in the field of analytical chemistry, offering high-resolution separation and analysis of complex mixtures with remarkable efficiency. This abstract provides a succinct overview of the key aspects and applications of CE in analytical chemistry. It covers the principles underlying CE, including electrokinetic phenomena, separation mechanisms, and detection methods. Furthermore, it highlights the versatility of CE in analyzing various analytes ranging from small ions to large biomolecules such as proteins, nucleic acids, and pharmaceutical compounds. The abstract also discusses recent advancements in CE technology, such as miniaturization, microfluidics integration, automation, and multimodal approaches, which have expanded the analytical capabilities and applicability of CE in diverse fields including pharmaceuticals, biotechnology, environmental science, and clinical diagnostics. Additionally, it emphasizes the significance of CE in addressing analytical challenges such as high throughput analysis, single-cell analysis, nanoparticle characterization, and biosensing.