Cancer Cell Lines: A Critical Tool in Cancer
*Corresponding Author:Received Date: Nov 01, 2024 / Published Date: Nov 30, 2024
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Abstract
Cancer cell lines are pivotal models in cancer research, facilitating the investigation of tumor biology, drug efficacy, and resistance mechanisms. This article explores the history and development of cancer cell lines, emphasizing their role in drug discovery and mechanistic studies. While they offer significant advantages, such as reproducibility and cost-effectiveness, cancer cell lines also have limitations, including genetic drift and a lack of tumor microenvironment representation. Future directions, including the use of organoids and patient-derived xenografts, aim to enhance the translational relevance of these models. Overall, cancer cell lines remain crucial in advancing our understanding of cancer and developing effective therapeutic strategies.