Journal of Alzheimers Disease & Parkinsonism
Open Access

Can SARs-CoV-2 Infect Nasal Epithelium and Cause Parkinson's Disease?

Mohsen Rafie^1*, Farhad Azadmehr², Mostafa Taheri³, Aylar Mansouri4⁴ and Valentyna Mahdi Naeim⁵

¹Department of Clinical Psychology, University of Semnan, Semnan, Iran

²Department of Medical-Surgical Nursing, Urmia University of Medical Sciences, Urmia, Iran

³Department of Critical Care Nursing, Tehran University of Medical Sciences, Tehran, Iran

⁴Department of Psychology, Johannes Kepler University Linz, Linz, Austria

⁵Department of Critical Care Nursing, Islamic Azad University, Ardabil, Iran

Received Date: Jan 02, 2023 / Published Date: Jan 31, 2023

Citation: Rafie M, Azadmehr F, Taheri M, Mansouri A, Naeim VM (2023) Can SARs-CoV-2 Infect Nasal Epithelium and Cause Parkinson's Disease?. J Alzheimers Dis Parkinsonism 13:560.DOI: 10.4172/2161-0460.1000560

Copyright: © 2023 Rafie M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Background: The main trigger for Parkinson's disease is a mutated version of a protein called alpha-synuclein. This protein accumulates in dopamine-producing neurons. COVID-19 can increase the risk of Parkinson's and other neurological diseases.

Materials and Methods: This research study was conducted by the library method.

Results: The results showed that the virus can cause neuroinflammation, which, as a predisposing event, predisposes the brain to overreaction to subsequent neurological events. This secondary neurological event can be anything from another viral infection to poisoning and even aging. A secondary neurological event triggers an abnormal brain response that leads to nerve degeneration and eventually Parkinson's disease. The results show that the SARS-CoV-2 virus as a neurotropic virus can enter brain tissue.

Conclusion: Therefore, the virus certainly has the potential to act as a predisposing event in increasing the risk of Parkinson's disease.

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