ISSN: 2475-7640

Journal of Clinical and Experimental Transplantation
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  • Research Article   
  • J Clin Exp Transplant 2016, Vol 1(1): 102
  • DOI: 10.4172/2475-7640.1000102

Calculating Additional Risk of Concomitant Laparoscopic Surgery in Living Kidney Donors: Cholecystectomy in Combination with Living Donor Nephrectomy

William F Parker1, Mark Siegler2, Peter Angelos2,3, Hoylan Fernandez5*, Sofia Medvedev4 and Giuliano Testa2,5
1Department of Internal Medicine, University of Chicago, Chicago, IL, USA
2MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL, USA
3Department of Endocrine Surgery, University of Chicago Medicine, Chicago, IL, USA
4University HealthSystem Consortium, Chicago, IL, USA
5Annette C and Harold C Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX, USA
*Corresponding Author : Hoylan Fernandez, Baylor University Medical Center, 3410 Worth Street, Suite 950, Dallas, Texas 75246, USA, Tel: (214) 820-6983, Fax: (214) 818-6491, Email: Hoylan.Fernandez@BaylorHealth.edu

Received Date: Jan 27, 2016 / Accepted Date: May 03, 2016 / Published Date: May 09, 2016

Abstract

Background: During the evaluation of a donor candidate for living kidney donation, occasionally a concomitant benign abdominal disease is diagnosed. Combining organ donation and surgical treatment of that disease could be beneficial to the donor. This paper quantified the additional risk to the donor if the two operations were combined. Study design: The clinical database of 155 academic medical centers and affiliated hospitals of University HealthSystem Consortium was used to predict the minimum expected surgical risk of a combined laparoscopic cholecystectomy and laparoscopic donor nephrectomy. Results: Our model predicted that a minimum of 8.64% of patients undergoing laparoscopic cholecystectomy at the same time as a donor nephrectomy would experience at least one complication. This represents an increase of 2.3% (relative risk=1.24) from the 6.34% risk for patients undergoing only the cholecystectomy. Conclusion: The estimation of increased risk is a necessary step to obtain informed consent from a donor offered or who wants to undergo multiple procedures simultaneously.

Keywords: Cholecystectomy; Decision analysis model; Living donor kidney transplantation; Nephrectomy; Relative risks; Risk assessment model; Surgical complications

Citation: Parker WF, Siegler M, Angelos P, Fernandez H, Medvedev S, et al. (2016) Calculating Additional Risk of Concomitant Laparoscopic Surgery in Living Kidney Donors: Cholecystectomy in Combination with Living Donor Nephrectomy. J Clin Exp Transplant 1: 102. Doi: 10.4172/2475-7640.1000102

Copyright: © 2016 Parker WF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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