By Modulating Microglia via the TLR4/Myd88/NLRP3/Casp1 Pathway, Endometrial Stem Cells Isolated by Menstrual Blood Suppress Neuroinflammation
Received Date: May 03, 2023 / Published Date: May 29, 2023
Abstract
Many neurological illnesses frequently result in neuroinflammation as a reaction. A possible therapeutic for conditions linked to neuroinflammation is mesenchymal stem cell therapy. Mesenchymal stem cell effects are debatable, and the underlying process is not well known. In the current study, a mouse model of neuroinflammation created by peripheral lipopolysaccharide injection received an intravenous transplant of endometrial stem cells generated from menstrual blood. Endometrial stem cell-derived conditioned media was used to cultivate microglial cells that had been exposed to lipopolysaccharide.
Citation: Campbel B (2023) By Modulating Microglia via the TLR4/Myd88/NLRP3/Casp1 Pathway, Endometrial Stem Cells Isolated by Menstrual Blood SuppressNeuroinflammation. Arch Sci 7: 152.
Copyright: © 2023 Campbel B . This is an open-access article distributed underthe terms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
Share This Article
Open Access Journals
Article Usage
- Total views: 1269
- [From(publication date): 0-2023 - Nov 08, 2024]
- Breakdown by view type
- HTML page views: 1173
- PDF downloads: 96