Abstract

Emerging zoonotic diseases pose significant threats to animal and human health, necessitating innovative biotechnological solutions in veterinary medicine. Advances in genetic engineering, molecular diagnostics, and vaccine development have revolutionized disease surveillance, prevention, and treatment. Biotechnology enables rapid pathogen detection through PCR-based assays, CRISPR technology, and next-generation sequencing. Novel vaccine strategies, including recombinant and mRNA-based vaccines, offer enhanced immunogenicity and targeted protection. Additionally, biopharmaceuticals and probiotics contribute to antimicrobial resistance mitigation, ensuring sustainable disease management. This review explores cutting-edge biotechnological interventions addressing zoonotic disease challenges, highlighting their implications for global One Health initiatives and veterinary public health.