Abstract

Biopharmaceutics plays a critical role in pediatric care, where the pharmacokinetics and pharmacodynamics of drugs can differ significantly from those observed in adults. This paper reviews the challenges and considerations in tailoring dosing strategies to optimize therapeutic outcomes for pediatric patients. Factors such as age, weight, organ maturity, and the unique disease profiles of children necessitate a careful evaluation of biopharmaceutical properties. We discuss various approaches to personalized dosing, including population pharmacokinetics, pharmacogenomics, and the use of innovative drug delivery systems. By understanding the nuances of drug behavior in children, healthcare providers can enhance treatment efficacy while minimizing adverse effects. Ultimately, this review underscores the importance of ongoing research and collaboration among clinicians, pharmacists, and researchers to improve biopharmaceutical applications in pediatric care.