Review Article
Biomatrices in Urethral Reconstruction
Long Zhang and Yajun Xiao*
Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei, China
- Corresponding Author:
- Yajun Xiao
Department of Urology, Union Hospital
Tongji Medical College, Huazhong University of Science and Technology
1277 Jiefang Road, Wuhan, Hubei 430022, China
Tel: +86 27 85351625
Fax: +86 27 85726970
E-mail: xiaoyjuh@163.com
Received Date: May 20, 2016; Accepted Date: May 31, 2016; Published Date: June 07, 2016
Citation: Zhang L, Xiao Y (2016) Biomatrices in Urethral Reconstruction. J Biotechnol Biomater 6:231. doi:10.4172/2155-952X.1000231
Copyright: © 2016 Zhang L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Urethral reconstruction is still a big challenge in urology. Traditionally, the penile skin or buccal mucosa was used as graft for replacement. However, the morbidity of the donor site was reported previously. Furthermore, there is a lack of an adequate autologous donor graft in many cases. The tissue engineered urethra may provide an alternative to the reconstruction. Herein, we reviewed the biomatrices for urethral substitution either in animal model or in clinical cases.