Abstract

Porous biomaterials can be additively manufactured with micro-architecture tailor-made to fulfill the stringent mechanic-biological necessities imposed through bone alternative implants. In a preceding investigation, we delivered structurally porous biomaterials, proposing electricity 5 instances more advantageous than commercially on hand porous materials, and tested their bone ingrowth functionality in an in vivo dogs model. While encouraging, the manufactured biomaterials confirmed geometric mismatches between their inner porous structure and that of its as-designed counterpart, as properly as discrepancies between anticipated and examined mechanical properties, troubles no longer utterly elucidated. In this work, we suggest a systematic strategy integrating computed tomography, mechanical testing, and statistical evaluation of geometric imperfections to generate statistical based totally numerical fashions of high-strength additively manufactured porous biomaterials.

Keywords: Biomaterial; Chitosan; Dental; Infection; Periodontitis; Prevention; Tissue engineering