Abstract

The emerging research field known as 3D bioprinting has emerged as a result of the deep cross-fertilization of 3D printing technology with numerous fields like mechanics, materials, and biomedicine.Extrusion 3D bioprinting, the most widely used technology for 3D bioprinting, can print biomaterials with a wide range of applicability and viscosities. In this review, we set up a composite hydrogel with glycerol as a multifunctional co-dissolvable and gelatin-oxidized nanocellulose as the lattice, as well as the ideal structure of the not entirely settled by material depiction.The hydrogel’s microstructure was examined with scanning electron microscopy (SEM), which revealed a three-dimensional porous
network structure with microporous pore sizes between 200 and 300 micrometers.According to infrared spectra, the addition of glycerol increased the hydrogel’s properties without affecting the gelatin-oxidized nanocellulose.In the meantime, the printed area is clear and structurally stable, and the composite hydrogel is suitable for extrusion-based 3D bioprinting due to its obvious shear-thinning and good mechanical properties.According to a number of findings, the hydrogel’s good pore structure, mechanical properties, and printable performance make it suitable for extrusion-based 3D bioprinting.A novel concept and material for 3D bioprinting are presented by this gelatin-oxidized nanocellulose
hydrogel, which also expands the material’s application range.