Abstract

The development of novel implantable devices represents a significant advancement in modern healthcare, offering innovative solutions to improve patient outcomes and quality of life. Biocompatibility and biofunctionality are critical considerations in ensuring the safe and effective integration of these devices within biological systems. This article explores key aspects of biocompatibility, encompassing material selection, surface modifications, and preclinical testing, as well as biofunctionality enhancements such as sensing capabilities, drug delivery systems, and neural interfaces. Challenges in implantable device technology, including immune responses and longevity issues, are discussed alongside future directions in smart implants, biomimetic materials, and regenerative therapies. By advancing these technologies, novel implantable devices hold promise for transforming healthcare delivery and enhancing patient care