Bilateral Internuclear Ophthalmoplegia, Deficiency and High Dose Administration of Vitamin D in Pediatric-Age Multiple Sclerosis: A Pediatric Case Report and Review of the Literature
Received Date: Apr 05, 2018 / Accepted Date: Apr 19, 2018 / Published Date: Apr 26, 2018
Abstract
Oculomotor Disorders (OMDs) can be seen as the initial symptoms or during the course of multiple sclerosis (MS). Bilateral internuclear ophthalmoplegia (BINO) is a rare observation as clinical MS onset. BINO and its prognostic value in pediatric-age MS patients are not absolutely known. Vitamin D deficiency is thought to be associated with an increased disease activity in MS and vitamin D is supposed to be a potent immunomodulatory agent. Vitamin D deficiency, its probable effects on the disease pathogenesis, and high dose administration to a pediatric age patient presented with BINO are discussed in this report.
Keywords: Oculomotor disorders; Multiple sclerosis; Bilateral internuclear ophthalmoplegia Vitamin D; Immunomodulatory agent
Citation: Genç Sel C, Altıaylık Ozer P, Savaş Erdeve S, Aksoy E, Dedeoğlu O, et al. (2018) Bilateral Internuclear Ophthalmoplegia, Deficiency and High Dose Administration of Vitamin D in Pediatric-Age Multiple Sclerosis: A Pediatric Case Report and Review of the Literature. Neurol Clin Therapeut J 2: 108.
Copyright: © 2018 Genç Sel C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
