Abstract

Globally, there is expanded rate of Parkinson’s disease (PD), which is the second most common age-related neurodegenerative malady. The right now accessible PD-therapeutics provides as it were symptomatic relief. Thus, there's an urgent need to plan a compelling and safe treatment technique for PD. The holistic approach of Ayurveda can be a potential effective strategy for treating PD. The integration of diverse pharmaceutical frameworks, such as modern bio-medicine and Ayurveda can be an effective strategy for treatment of complex diseases, including PD. The mode of action of methanolic herbal extracts was evaluated utilizing the Caenorhabditis elegans BZ555 and NL5901 strains, which can be used to show the two main hallmarks of PD, namely degeneration of dopaminergic neurons and aggregation of α-synuclein protein.