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Assessment of Hematological and Biochemical Markers in the Early post-Burn Period for Predicting Recovery and Mortality in Animals with Burn Injuries | OMICS International| Abstract
ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
Open Access

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  • Research Article   
  • J Clin Exp Pathol 2018, Vol 8(2): 343
  • DOI: 10.4172/2161-0681.1000343

Assessment of Hematological and Biochemical Markers in the Early post-Burn Period for Predicting Recovery and Mortality in Animals with Burn Injuries

Atef Mohammed Khalil1*, Obeid Mahmoud Shanab2, Gian Franco Zannoni3 and Eisa Mohamed Hegazy3
1Department of Pathology and Clinical Pathology, South Valley University, Qena, Egypt
2Department of Biochemistry, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt
3Department of Dermatology Venereology and Andrology, Faculty of Medicine, South Valley University, Qena, Egypt
*Corresponding Author : Atef Mohammed Khalil MD, Department of Pathology and Clinical Pathology, South Valley University, Qena, Egypt, Tel: 0200120074609, Fax: 020963211223, Email: Atef-clpatho@vet.svu.edu.eg

Received Date: Apr 07, 2018 / Accepted Date: May 07, 2018 / Published Date: May 14, 2018

Abstract

Here we investigate hematological and biochemical alterations in the burn animals. The values of these parameters are very important in allowing the veterinarians to know how the animal body is responding to the different therapies that being provided? And this will help the veterinary medical staff for proper management with less morbidity and mortality. Three burned animals were admitted to the University's Veterinary Hospital, Faculty of Veterinary Medicine, South Valley University. They were suffering from second to third degree burn injury. Blood samples were collected after 48 h post burn for hematological and biochemical analyses. For the hematological parameters, RBCs count, hemoglobin (Hb) concentration, packed cell volume (PCV%) and platelets count exhibited significant decreases in burnt animals in comparison to healthy control animals. Burns also induced increases in WBCs count, MCV and MCH in comparison to the controls. For the differential leukocytic count, lymphocytosis and neutrophilia were recorded in burned animals. For biochemical parameters, liver enzymes activities as well as serum creatinine and urea were significantly increased when compared with the control animals. The total serum protein and albumin of burn animals revealed significant decrease. The serum electrolytes, serum sodium showed a significant decrease while serum potassium showed significant increase.

Keywords: Burns; Biochemical; Hematological; Electrolytes; Health care team; Proper management

Citation: Khalil MA, Shanab OM, Zannoni GF, Heygazy EM (2018) Assessment of Hematological and Biochemical Markers in the Early post-Burn Period for Predicting Recovery and Mortality in Animals with Burn Injuries. J Clin Exp Pathol 8:343. Doi: 10.4172/2161-0681.1000343

Copyright: © 2018 Khalil AM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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