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Applications of Microdosing in Clinical Pharmacology: A Step Toward Personalized Medicine and Accelerated Drug Development

Birhanu Tabo*
International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Nigeria
*Corresponding Author: Birhanu Tabo, International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Nigeria, Email: birhanutabo123@gmail.com

Received Date: Nov 01, 2024 / Published Date: Nov 29, 2024

Citation: Birhanu T (2024) Applications of Microdosing in Clinical Pharmacology: A Step Toward Personalized Medicine and Accelerated Drug Development Clin Pharmacol Biopharm, 13: 512.

Copyright: © 2024 Birhanu T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Microdosing, the practice of administering sub-therapeutic doses of a drug to study its pharmacokinetics, pharmacodynamics, and safety profile, has emerged as a promising tool in clinical pharmacology. It offers a unique approach to understanding drug behavior in humans without exposing participants to the risks associated with higher doses. This approach has the potential to significantly accelerate drug development by enabling early-phase clinical testing, optimizing dose selection, and providing valuable data for personalized medicine. Microdosing allows researchers to gather crucial information on drug interactions, absorption, distribution, metabolism, and excretion (ADME), while also minimizing costs and time in the early stages of clinical trials. This review discusses the applications of microdosing in clinical pharmacology, its role in personalized medicine, and its potential to streamline drug development processes

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