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Hindi Antidiabetic Activity of Vincarosea Extracts in Alloxan-Induced Diabetic Rats
*Corresponding Author:
Copyright: © 2020 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The present study was carried out to evaluate the antidiabetic activity of Vincaroseamethanolic whole plant extracts in alloxan induced diabetic rats for 14 days. The methanolic whole plant extract at high dose (500mg/kg) exhibited significant anti-hyperglycemic activity than whole plant extract at low dose (300mg/kg) in diabetic rats. The methanolic extracts also showed improvement in parameters like body weight and lipid profile as well as regeneration of β-cells of pancreas in diabetic rats. Histopathological studies reinforce the healing of pancreas, by methanolic Vincarosea extracts, as a possible mechanism of their antidiabetic activity.
