Research Article
An Open Comparative Randomized Clinical Study of Plant Based Drugs Embelia Robusta Roxb and Mallotus Philippinensis Muell on Intestinal Parasites
Shishira Bharadwaj1, Shraddha Nayak2* and Joshi VK31Clinical Associate, Department of Hospital Medicine, Cleveland Clinic, USA
2Professor, BM Kankanawady Ayurved Mahavidyalaya, Belgaum, India
3Professor, Banaras Hindu University, India
- *Corresponding Author:
- Shraddha Nayak
Professor, BM Kankanawady Ayurved Mahavidyalaya
Belgaum, India
E-mail: shradhaayu1@rediffmail.com
Received date: April 18, 2013; Accepted date: June 03, 2013; Published date: June 05, 2013
Citation: Bharadwaj S, Shraddha N, Joshi VK (2013) An Open Comparative Randomized Clinical Study of Plant Based Drugs Embelia Robusta Roxb and Mallotus Philippinensis Muell on Intestinal Parasites. J Gastroint Dig Syst 3:122. doi: 10.4172/2161-069X.1000122
Copyright: © 2013 Bharadwaj S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Background: Intestinal parasites are common cause of morbidity.
Aim: To compare the efficacy and safety of two plant based drugs Embelia robusta Roxb and Mallotus philippinensis Muell on intestinal parasites.
Methods: Forty Patients exhibiting symptoms of parasitic infection were diagnosed and confirmed by stool test. They were then randomized to either Embelia in a dose of 5 g or Mallotus in dose of 1 g with honey and jaggery as adjuvant respectively. Drugs were administered for a period of one week and follow-up was carried in 15 days and thereafter a month to observe symptomatic relief and presence or absence of ova/cyst in stool sample examination.
Results: Symptomatic relief was found in Mallotus while some symptoms still persisted with Embelia. Embelia robusta had 40% cure rate while Mallotus had 70% cure rate, but both the drugs did not result in any adverse effects.
Conclusions: It was observed that Mallotus philippinensis had better efficacy.