Review Article
An Emerging Model of Word Retrieval in Preclinical Alzheimer's Disease
Vanja Kljajevic*
University of the Basque Country (UPV/EHU) & IKERBASQUE, Basque Foundation for Science, Spain
- Corresponding Author:
- Vanja Kljajevic
Ikerbasque Research Fellow
University of the Basque Country (UPV/EHU) & IKERBASQUE
Basque Foundation for Science, Spain
Tel: 34 608 242 256
E-mail: vanja.kljajevic@gmail.com
Received date: March 08, 2016; Accepted date: March 17, 2016; Published date: March 24, 2016
Citation: Kljajevic V (2016) An Emerging Model of Word Retrieval in Preclinical Alzheimer’s Disease. J Alzheimers Dis Parkinsonism 6:225. doi:10.4172/2161-0460.1000225
Copyright: © 2016 Kljajevic V. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Word retrieval deficit in persons on the Alzheimer’s disease (AD) spectrum has been investigated mostly in AD dementia and, to a smaller degree, in patients with mild cognitive impairment. However, recent evidence suggests that changes in word retrieval abilities are also present in persons at the presumably earliest stage of AD, i.e. in preclinical AD. Considering this evidence as well as previous findings on word retrieval difficulties in cognitively healthy elderly persons, the present paper outlines a novel model of word retrieval in Alzheimer’s disease that is emerging from research in these two fields.