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Hindi Case Report
Amniotic Band Syndrome: A Case Series
| Srinivasan H1*, Dhungel P1, Harper T2 and Lampley C3 | |
| 1Department of Pediatrics, Mount Sinai Hospital, Chicago, IL, USA | |
| 2Department of Pathology, Mount Sinai Hospital, Chicago, IL, USA | |
| 3Department of Obstetrics and Gynecology, Mount Sinai Hospital, Chicago, IL, USA | |
| Corresponding Author : | Dr Hari Srinivasan Mount Sinai hospital. Pediatrics 15th and California, Chicago, IL 60608, USA Tel : 7732575392 E-mail: hari.srinivasan@sinai.org |
| Received July 11, 2014; Accepted September 09, 2014; Published September 15, 2014 | |
| Citation: Srinivasan H, Dhungel P, Harper T, Lampley C (2014) Amniotic Band Syndrome: A Case Series. J Preg Child Health 1:109. doi: 10.4172/2376-127X.1000109 | |
| Copyright: © 2014 Srinivasan H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
Three cases of amniotic band syndrome (ABS) were studied to highlight the clinicopathologic characteristics. The diagnosis was based on the following manifestations: cranio facial clefts; limb body wall defects and amniotic band attachment. All three cases were stillborn and associated with defects in the central nervous system, heart or gastrointestinal system. Phenotypic features included craniofacial clefting, thoracoabdominoschisis, amputation, ring constriction, amniotic band adhesion, placental adhesions, and internal malformations. When analyzing the phenotype in relation to their etiology, it was found that amniotic disruption, vascular disruption or genetic disruption could explain the amniotic band syndrome/limb body wall complexes, alone or in combinations.
