Abstract

Substance Use Disorders (SUDs) remain a critical global health issue, causing significant morbidity and mortality. Advances in neuroscience, psychology, and pharmacology have illuminated new pathways for understanding and treating these disorders. This article synthesizes contemporary research on SUDs, exploring the interplay of genetic, environmental, and neurobiological factors. It also examines novel therapeutic approaches, including precision medicine, psychotherapeutic innovations, and public health interventions. The paper concludes with recommendations for integrating scientific discoveries into policy and practice, emphasizing a multidisciplinary approach to mitigate the impact of SUDs.