ISSN: 2381-8727

International Journal of Inflammation, Cancer and Integrative Therapy
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  • Case Study   
  • Int J Inflam Cancer Integr Ther,
  • DOI: 10.4172/2381-8727.1000209

Advances in mRNA Nanomedicines for the Treatment of Malignant Brain Tumours

Banzhou Zang*
Department of Oncology, People's Hospital of Shenzhen Baoan District, The Second Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, 518055, China
*Corresponding Author : Banzhou Zang, Department of Oncology, People's Hospital of Shenzhen Baoan District, The Second Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, 518055, China, Email: banzang@qq.com

Received Date: Jan 25, 2023 / Published Date: Feb 28, 2023

Abstract

Currently, nasty brain excrescences are still substantially murderous conditions with poor prognostic and a clinical standard survival rate of smaller than 2 times after remedial intervention. It’s delicate to achieve complete absolution of brain excrescences due to blood-brain hedge (BBB) and a lack of effective medicine delivery systems to targeted transportation of brain excrescence drugs [1]. Nanoparticle delivery systems have shown graces including stability and high carrier capacity for the transportation of different medicines to treat brain excrescences. The operation of mRNA
nanomedicines brings in great pledge not only in COVID-19, but also for nasty brain excrescence immunotherapy.The applicable delivery system facilitates mRNA delivery effectiveness and enhances the vulnerable response successfully, for optimal treatment issues on nasty brain excrescences [2]. Herein, we do an streamlined review on the development of mRNA nanomedicines for nasty brain cancer treatment. We concentrate on how to design mRNA-loaded nanoparticle-grounded delivery systems with optimized pharmacokinetics and pharmacodynamics for effective remedy of brain cancers. In addition, we point out the challenges and results for farther development of mRNA nanomedicines for brain cancer remedy. We hope this review would stimulate interest among experimenters with different backgrounds and expedite the restatement from bench to bedside for the mRNA nanomedicines [3].

Citation: Zang B (2023) Advances in mRNA Nanomedicines for the Treatment ofMalignant Brain Tumours. Int J Inflam Cancer Integr Ther, 10: 209. Doi: 10.4172/2381-8727.1000209

Copyright: © 2023 Zang B. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.

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