Abstract

Recent advancements in targeted drug delivery systems have revolutionized the field of medicine by enhancing therapeutic efficacy while minimizing adverse side effects. These innovative approaches utilize various nanocarriers, bioconjugates, and stimuli-responsive systems to deliver drugs specifically to diseased tissues, improving treatment outcomes in conditions such as cancer, autoimmune disorders, and chronic diseases. This review highlights the latest developments in targeted delivery technologies, including liposomes, nanoparticles, and antibody-drug conjugates, and discusses their mechanisms of action, benefits, and challenges. Additionally, it examines the role of personalized medicine in optimizing drug delivery strategies, emphasizing the importance of patient-specific factors in treatment design. By focusing on localized therapy and reducing systemic exposure, these advancements promise to improve patient compliance and enhance overall therapeutic success.