Abstract

Kidney transplantation remains the optimal treatment for end-stage renal disease, offering improved quality of life and increased longevity for recipients. This review article explores the latest trends and future directions in kidney transplantation, shedding light on the remarkable progress achieved in recent years and the challenges that persist. Advancements include the rise of living donor kidney transplants, the development of personalized immunosuppressive regimens, innovative cross-match techniques, and the utilization of ex vivo perfusion to assess and preserve donor organs. However, challenges such as organ shortages, rejection risks, long-term complications, and access barriers remain. The future of kidney transplantation holds promise in regenerative medicine, immunomodulation, precision medicine, and the potential for artificial organs. Collaborative efforts among healthcare professionals, researchers, and policymakers are vital to improving outcomes and expanding access to this life-saving procedure.