Review Article
Acute Hepatitis C Virus Infection and Directly Acting Anti-Hepatitis C Virus Drugs
Omkolsoum M Alhaddad1*, Maha M Elsabaawy1, Omar Elshaarawy1, Dalia M Elsabaawy2 and Tarek Mansour31Department of Hepatology, National Liver Institute, Menoufia University, Egypt
2Department of Community Medicine, National Liver Institute, Menoufia University, Egypt
3Department of Internal Medicine, Ain Shams University, Egypt
- *Corresponding Author:
- Omkolsoum M Alhaddad
Department of Hepatology, National Liver Institute
Menoufia University, Egypt
Tel: 002 01001779069
E-mail: dromkolsoum@yahoo.com
Received date: January 23, 2017; Accepted date: March 29, 2017; Published date: April 5, 2017
Citation: Alhaddad OM, Elsabaawy MM, Elshaarawy O, Elsabaawy DM, Mansour T (2017) Acute Hepatitis C Virus Infection and Directly Acting Anti-Hepatitis C Virus Drugs. J Gastrointest Dig Syst 7:496. doi: 10.4172/2161-069X.1000496
Copyright: © 2017 Alhaddad OM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The best of care of Acute hepatitis C (AHC) infections in the evolving era of all oral directly acting antiviral drugs (DDAs) needs revision. The inevitable chronic liver disease in 80% of AHC infections justifies the advent of DDAs that expectedly will guarantee high cure rates. Unlike interferons, the short and ultra-short all oral DDAs regimens had revolutionized treatment strategies with better adherence and fewer complications. However, the costly price of DAAs added to the average expertise is still contrarily active. Up-to-date, studies concerning DAAs treatment for AHC mono-infection are sparse; indeed this represents an unmet need in modern AHC management.