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Editorial

Acute Fatty Liver of Pregnancy: A Case Report and Literature Review

Nilanchali Singh* and Pragati Meena
Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India
Corresponding Author : Nilanchali Singh
Department of Obstetrics and Gynecology
University College of Medical Sciences and Guru Tegh Bahadur
Hospital, Delhi, India
Tel: 919811343168
E-mail: nilanchalisingh@gmail.com
Received: June 25, 2015; Accepted: June 27, 2015; Published: June 30, 2015
Citation: Singh N, Meena P (2015) Acute Fatty Liver of Pregnancy: A Case Report and Literature Review. J Preg Child Health 2:e118. doi: 10.4172/2376-127X.1000e118
Copyright: © 2015 Nilanchali S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Acute Fatty Liver of Pregnancy (AFLP) is a rare, catastrophic disease affecting women in pregnancy. It usually occurs in the third trimester or post-partum period. It is usually a diagnosis of exclusion and a strong index of suspicion can lead to timely diagnosis. Delay in diagnosis is associated with morbid complications with high mortality. We report a case of 22 years old lady with 36 weeks pregnancy presented with malaise, nausea, vomiting and jaundice. A clinical diagnosis of acute fatty liver of pregnancy was made. Although early Cesarean section was performed, postoperative course was complicated by acute hepatic encephalopathy with hepatorenal shutdown and coagulopathy. Despite intensive management in critical care, the patient expired.

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