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Hindi Case Report
Acrokeratosis Verruciformis of Hopf (Hopf Disease)
| Hussein Salman1* and Waiel Osman2 | ||
| 1Dermatology Clinic, Khartoum Teaching Hospital, Khartoum, Sudan | ||
| 2Registrar of dermatology, Khartoum Teaching Hospital, Khartoum, Sudan | ||
| Corresponding Author : | Hussein Salman Dermatology Clinic Khartoum Teaching Hospital Khartoum, Sudan Tel: +249123094485 E-mail: dardaka@gmail.com |
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| Received December 12, 2013; Accepted January 25, 2014; Published January 30, 2014 | ||
| Citation: Salman H, Osman W (2014) Acrokeratosis Verruciformis of Hopf (Hopf Disease). J Infect Dis Ther 2:128. doi:10.4172/2332-0877.1000128 | ||
| Copyright: © 2014 Salman H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | ||
Related article at Pubmed Scholar Google |
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Abstract
Acrokeratosis verruciformis of Hopf is an autosomal dominant genodermatosis usually presenting with multiple planar wart-like lesions, typically observed on the dorsum of the hands, feet, elbows, and knees. The disease is very rare and the pathogenesis remains unknown. Considerable controversy surrounds the nature and relationship of acrokeratosis and Darier disease and whether they are manifestations of one genetic abnormality. We describe the case of a 40-year-old man seen in our clinic with skin-coloured, flat, warty papules localized to the dorsum of the hands and feet. Both clinical and histological findings were compatible with acrokeratosis verruciformis. We also review the disease, particularly its relation with Darier Disease and therapeutical options.
