Acinic Cell Carcinoma of the Breast (ACC): Morphological and Molecular Features of Rare Breast Cancer
Received Date: Jun 16, 2023 / Accepted Date: Jul 10, 2023 / Published Date: Jul 17, 2023
Abstract
Acinic Cell Carcinoma of the breast (ACC) is a very rare subtype of breast cancer, being of bland cellular morphology, but having a triple-negative phenotype. Usually, it was thought to be indolent, but a few cases have been reported highly aggressive. The molecular studies showed similar features in diagnosing to the Triple-Negative Breast Cancer (TNBC), which usually had the aggressive clinical course. This mini review comprehensively summarizes the recent literature on the molecular features of this rare breast cancer. We try to explain why some ACC have not the indolent course as we thought previously.
Keywords: Acinic Cell Carcinoma (ACC); Molecular features; Cytoplasm; Triple-Negative Breast Cancer (TNBC)
Citation: Min L, Hongkai Z (2023) Acinic Cell Carcinoma of the Breast (ACC): Morphological and Molecular Features of Rare Breast Cancer. Diagnos Pathol Open 8:217. Doi: 10.4172/2476-2024.8.1.217
Copyright: © 2023 Min L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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