Review Article
Achalasia Cardia Recent Advances in Diagnosis and Endoscopic Management
Zaheer Nabi* and Duvvur Nageshwar ReddyAsian Institute of Gastroenterology, Hyderabad, Telangana, India
- *Corresponding Author:
- Zaheer Nabi
Consultant, Asian Institute of Gastroenterology
Gastroenterology, 6-3-661, Somajiguda
Hyderabad, Telangana 500082, India
Tel: 919573058810
E-mail: zaheernabi1978@gmail.com
Received date: October 21, 2015; Accepted date: January 11, 2016; Published date: January 20, 2016
Citation: Nabi Z, Reddy DN (2016) Achalasia Cardia – Recent Advances in Diagnosis and Endoscopic Management. J Gastrointest Dig Syst 6:393. doi:10.4172/2161-069X.1000393
Copyright: © 2016 Nabi Z, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Achalasia Cardia is a rare neurodegenerative disorder of esophagus resulting in defective peristalsis and impaired relaxation of lower esophageal sphincter. The exact etiopathogenesis of achalasia is not known. Achalasia is associated with significant morbidity and impaired quality of life. The standard of care in patients with achalasia has been pneumatic balloon dilatation and laparoscopic heller's myotomy. Recent advancements in the diagnosis and endoscopic management have greatly improved the outcomes of this disorder. Subtyping of esophageal motility disorders with high resolution manometry has served to predict treatment outcomes and plan appropriate treatment. Per oral endoscopic myotomy (POEM) is an novel minimally invasive treatment option for all types of achalasia cardia. Short and mid term efficacy are excellent. Randomized trials are required to confirm its superiority over the currently established treatment modalities.