ISSN: 2329-910X

Clinical Research on Foot & Ankle
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  • Short Commentary   
  • Clin Res Foot Ankle, Vol 5(2): 241
  • DOI: 10.4172/2329-910X.1000241

A Short Commentary about Efficacy of an Flowable Matrix in the Treatment of Diabetic Foot Ulcers

Campitiello F, Mancone M*, Della Corte A, Guerniero R and Canonico S
Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", , Italy
*Corresponding Author : Mancone M, Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", Italy, Tel: 3388212431, Email: manfredi.mancone@alice.it

Received Date: Jul 06, 2017 / Accepted Date: Jul 22, 2017 / Published Date: Dec 27, 2016

Abstract

The authors aimed to evaluate the efficacy of an advanced wound matrix (Integra Flowable Wound Matrix, Integra Life Science Corp, Plainsboro, NJ, USA) for treating wounds with irregular geometries versus a wet dressing in sixty patients with diabetic foot ulcers (Grades 3 Wagner ulcer). A randomized clinical trial was conducted in the General Surgery Unit and Geriatric of the Second University of Naples, Italy, in the last 12 months. Forty-seven cases of diabetic foot ulcers were equally and randomly divided into two groups: in a group treated with a wet dressing and expected closure by secondary intention; in another group the lesions were filled with Integra Flowable Wound Matrix and surgical wound edges were either approximated with stitches. The complete healing rate valued at 6 weeks, in the whole study population was 69.56% (Integra Flowable Wound Matrix group, 86.95%, control group, 52.17%; P=0.001). Amputation and re-hospitalization rates were higher in the control group compared to Integra Flowable Wound Matrix group. Therefore the difference was statistically significant.

This new porous matrix, allows a closure for the first intention of the lesion by reducing healing time and the demolition surgery. An advanced wound matrix is not associated with side effects, is well tolerated. Ease of use, absence of adverse effects, and a minimal invasive approach by primary intention closure of the lesion, make it appropriate in the management diabetic foot ulcers.

Keywords: Diabetic foot ulcers; Tunneling lesions; Biomaterial; Flowable matrix

Citation: Campitiello F, Mancone M, Corte AD, Guerniero R, Canonico S (2017) A Short Commentary about Efficacy of an Flowable Matrix in the Treatment of Diabetic Foot Ulcers. Clin Res Foot Ankle 5: 241. Doi: 10.4172/2329-910X.1000241

Copyright: © 2017 Campitiello F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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