Abstract

Background and aim: Genome wide affiliation thinks about have scaled up both in terms of test measure and run of complex disarranges examined, but these have clarified moderately small phenotypic change. Of the a few reasons, phenotypic heterogeneity appears to be a likely supporter for lost out hereditary affiliations of huge impacts. Ayurveda, the conventional Indian framework of medication is one such device which embraces an all-encompassing profound phenotyping approach and classifies people based on their body constitution/prakriti. We hypothesized that Ayurveda based phenotypic stratification of sound and infected people will permit us to realize much wanted homogeneous cohorts which would encourage location of hereditary affiliation of huge impacts. In this verification of concept think about, we performed a genome wide affiliation testing of clinically analyzed rheumatoid joint pain patients and solid controls, which were re-phenotyped into Vata, Pitta and Kapha transcendent prakriti sub-groups.