Abstract

Antimicrobial efficacy of complex-type chlorine-based disinfectant cleaner RUBYSTA® (RST) consisting mainly of potassium peroxymonosulfate against pathogenic microoganisms such as Methicillin-Resistant Staphylococcus aureus (MRSA), Multidrug Resistant Pseudomonas aeruginosa (MDRP), Feline Calicivirus (FCV) as a surrogate for norovirus, and Bovine Viral Diarrhea Virus (BVDV) as a surrogate for hepatitis C virus. In the suspension test, 1% RST caused 4log₁₀ or more reduction in MRSA, MDRP and FCV in 1 minute in the presence of 0.03% bovine serum albumin. The viral inactivation efficacy of RST was better than that of NaOCl at the same available chlorine concentration. In the immersion test using BVDV adhering to a stainless carrier, the viral inactivation efficacy of 0.1% NaOCl and 1% RST in 1 minute was 0.9 log10 reduction and 3.3 log₁₀ reduction, respectively. Furthermore, in the wipe test, 1% RST immersion wipe caused 4.5 log₁₀ or more reduction in FCV. The present findings suggest that RST is effective for daily disinfection and cleaning in the hospital environment.

Keywords: Potassium peroxymonosulfate; Methicillin-Resistant Staphylococcus aureus (MRSA); Multidrug Resistant Pseudomonas aeruginosa (MDRP); Feline Calicivirus (FCV); Bovine Viral Diarrhea Virus  (BVDV)