Abstract

This study was carried out on 100 animals (79 cows and 21 buffaloes) to investigate the incidence and the growth patterns of granulosa cell tumors based on histopathological characteristics. Granulosa cell tumors were prevalent in 49 out of 73 cases having ovarian lesions. Unilateral localization was the most common. Different growth patterns evoked the idea of establishment of a new classification of bovine ovarian granulosa cell tumors. Ten patterns were recognized including 1- Single focal pattern, 2- Single focal pattern having sertoli-like cells, 3- Single focal pattern with theca-like cells around, 4- Multifocal separated pattern, 5- Multifocal coalesced pattern, 6- Multifocal and cystic pattern, 7- Unifocal multicystic pattern, 8- Multifocal with clusters pattern (rosettes), 9- Call Exner's cell formation, and 10- Adenomatous hyperplasia of rete ovary.

Keywords: Ovary; GCT; Cows; Buffaloes; Histopathology; Autoflourescence