ISSN: 2161-0681

Journal of Clinical & Experimental Pathology
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  • Case Report   
  • J Clin Exp Pathol,

A Case of Vas Deferens Lesion with Features of Vasitis Nodosa and Mesothelial Proliferationc

Wenyi Luo* and Beth Raju
Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma, United States
*Corresponding Author : Wenyi Luo, Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma, United States, Tel: +14052717864, Email: Wenyi-Luo@ouhsc.edu

Received Date: Nov 09, 2020 / Accepted Date: Nov 23, 2020 / Published Date: Nov 30, 2020

Abstract

Background: Vasitis nodosa is a nodular lesion within the vas deferens that is characterized by a benign glandular proliferation of the vas deferens epithelium mixed with sperm and chronic inflammation. It is considered a reactivecondition caused by increased intraluminal pressure. Problems in diagnosis can arise when atypical morphologic features are present.

Case presentation: A 25-year old African American male status post vasectomy was diagnosed with obstructive azoospermia and elected to undergo a vasovasostomy. The morphology of the resected specimen was consistent with vasitis nodosa, but the proliferative epithelial cells also demonstrated the phenotype of mesothelium by immunohistochemistry.

Conclusion: This is the first reported case of vas deferens lesion with both features of vasitis nodosa and mesothelial proliferation, and it may give insight into the cellular origin of vasitis nodosa.

Keywords: Vasitis nodosa; Biphenotypic; Mesothelium

Citation: Luo W, Raju B (2020) A Case of Vas Deferens Lesion with Features of Vasitis Nodosa and Mesothelial Proliferation. J Clin Exp Pathol 10: 386.

Copyright: © 2020 Luo W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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