ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
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  • Opinion   
  • J Gastrointest Dig Syst, Vol 14(5)
  • DOI: 10.4172/2161-069X.1000840

The Role of Digestive Enzymes in Managing Gastrointestinal Disorders

Ruby Olivia*
*Corresponding Author: Ruby Olivia, Department of Gastroenterology, University of Alicante, Spain, Email: ruby_o@gmail.com

Received: 01-Oct-2024 / Manuscript No. JGDS-24-152384 / Editor assigned: 03-Oct-2024 / PreQC No. JGDS-24-152384 (PQ) / Reviewed: 17-Oct-2024 / QC No. JGDS-24-152384 / Revised: 22-Oct-2024 / Manuscript No. JGDS-24-152384 (R) / Published Date: 29-Oct-2024 DOI: 10.4172/2161-069X.1000840

Introduction

Symptoms like bloating, gas, and indigestion often result from incomplete digestion. By ensuring complete food breakdown, enzymes alleviate these discomforts, promoting smoother digestion. Proper digestion reduces the strain on the immune system, as undigested food can lead to bacterial fermentation and toxin production in the gut, potentially weakening immune health. Many adults experience reduced lactase production, leading to lactose intolerance, characterized by bloating, gas, and Diarrhea upon consuming dairy. Conditions like EPI or cystic fibrosis impact the pancreas's ability to release enzymes, causing nutrient malabsorption and often requiring enzyme supplementation. As individuals age, natural enzyme production decreases, making older adults more prone to digestive issues. Supplementing enzymes can often aid in maintaining digestive health as one ages. Enzyme supplements are increasingly used to address digestive enzyme insufficiencies. These supplements typically contain a mix of amylase, protease, and lipase, and some are specially formulated with lactase, cellulase (for fiber digestion), or bromelain and papain (plantbased proteases). Supplements help ensure complete food breakdown, maximizing nutrient absorption and preventing deficiencies. By promoting full digestion, enzyme supplements alleviate common symptoms like bloating and gas. People on high-protein diets, vegan diets, or those with lactose intolerance may benefit from supplements tailored to their dietary needs.

Description

Patients with conditions like pancreatitis, cystic fibrosis, or Irritable Bowel Syndrome (IBS) may find symptom relief with enzyme supplementation, though they should always consult a healthcare professional. Derived from the pancreas of pigs or cows, these enzymes mimic human enzymes closely. Sourced from fruits like pineapple (bromelain) and papaya (papain), these enzymes are suitable for vegans. Fermented by bacteria or fungi, these enzymes are stable across a wide pH range, allowing for effectiveness in different parts of the digestive tract. Though generally safe for most individuals, enzyme supplements should be used under medical supervision, particularly for those with underlying health conditions or allergies. High doses of certain enzymes can lead to side effects such as nausea, abdominal pain, or allergic reactions. Studies indicate that digestive enzyme supplements can improve symptoms in individuals with enzyme deficiencies or digestive conditions. However, not everyone needs supplementation, as healthy individuals with adequate enzyme production typically derive sufficient enzyme activity from their own bodies. Emerging research in digestive enzymes focuses on engineering enzymes for specific health conditions, advancing treatment options for enzyme deficiencies, and improving the efficacy of enzyme supplements. Innovations in enzyme stability and targeted delivery are among the developments anticipated to enhance enzyme therapy outcomes.

Conclusion

Moreover, the relationship between enzymes and gut health continues to be explored, particularly regarding how enzymes affect the gut microbiome and overall metabolic health. The role of enzymes in managing chronic diseases, like diabetes and inflammatory bowel disease, highlights their therapeutic potential beyond conventional digestion support. Digestive enzymes are indispensable for effective digestion and overall health, facilitating the breakdown of food into nutrients that fuel the body. Enzyme deficiencies can lead to digestive distress, malabsorption, and broader health implications, but enzyme supplements offer a viable solution for those with digestive issues or specific enzyme insufficiencies. As research progresses, understanding digestive enzymes’ complexities will continue to improve, shedding light on new therapeutic possibilities and enhancing dietary health.

Acknowledgement

None.

Conflict of Interest

The authors declare that they have no competing interests.

Citation: Olivia R (2024) The Role of Digestive Enzymes in Managing Gastrointestinal Disorders. J Gastrointest Dig Syst 14:840. DOI: 10.4172/2161-069X.1000840

Copyright: © 2024 Olivia R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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